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Alopecia Areata: An Autoimmune Hair Loss Challenge, New Drug Offers Treatment Breakthrough

Alopecia Areata (commonly known as "spot baldness") is an autoimmune disease. (Photo / Provided by Heho Health)
Alopecia Areata (commonly known as "spot baldness") is an autoimmune disease. (Photo / Provided by Heho Health)

Alopecia areata, also known as "spot baldness," is an autoimmune disease that occurs when the immune system mistakenly attacks healthy hair follicles, leading to hair loss in coin-sized round patches on the scalp. In severe cases, it can affect eyebrows, eyelashes, and even body hair. Dr. Lin Song-Ran, president of the Taiwan Dermatological Association, states that severe patients may develop total scalp or body hair loss, and about 2% of the population experiences this condition in their lifetime.

According to Taiwan's National Health Insurance database, the actual number of alopecia areata patients may reach 40,000 to 50,000. However, due to a lack of awareness, many people miss the opportunity for early treatment. The condition is linked to an overactive immune cycle involving interferons, interleukins, and JAK kinases. Treatment options include topical immune modulators, transdermal sensitization, and systemic therapies, which must be tailored to each individual's condition.Treating alopecia areata requires perseverance. (Photo / Provided by Heho Health)

The latest oral JAK inhibitors have become a breakthrough treatment, receiving approval from both the U.S. FDA and Taiwan TFDA. This new medication, launched in Taiwan this year, offers new hope for patients with extensive alopecia areata. Dr. Lin emphasizes that hair follicles are not permanently damaged, and about 80% of patients have the potential to regrow hair, though recurrences are possible.Stress can also cause hair loss. (Photo / Provided by Heho Health)

If you suspect alopecia areata, it is crucial to seek medical attention early. With proper diagnosis and personalized treatment plans, patients can effectively manage the condition and improve their quality of life.

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